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p53 signaling is involved in leptin-induced growth of hepatic and breast cancer cells

Leptin, an adipokine predominantly produced from adipose tissue, is well known to induce tumor growth. However, underlying molecular mechanisms are not established yet. While p53 has long been well recognized as a potent tumor suppressor gene, accumulating evidence has also indicated its potential r...

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Detalles Bibliográficos
Autores principales: Shrestha, Mohan, Park, Pil-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014995/
https://www.ncbi.nlm.nih.gov/pubmed/27610035
http://dx.doi.org/10.4196/kjpp.2016.20.5.487