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Automatic Construction of Predictive Neuron Models through Large Scale Assimilation of Electrophysiological Data

We report on the construction of neuron models by assimilating electrophysiological data with large-scale constrained nonlinear optimization. The method implements interior point line parameter search to determine parameters from the responses to intracellular current injections of zebra finch HVC n...

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Detalles Bibliográficos
Autores principales: Nogaret, Alain, Meliza, C. Daniel, Margoliash, Daniel, Abarbanel, Henry D. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015021/
https://www.ncbi.nlm.nih.gov/pubmed/27605157
http://dx.doi.org/10.1038/srep32749