Cargando…

Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma

In neuroblastoma (NB), one of the most common paediatric solid tumours, activation of anaplastic lymphoma kinase (ALK) is often associated with poor outcomes. Although genetic studies have identified copy number alteration and nonsynonymous mutations of ALK, the regulatory mechanism of ALK signallin...

Descripción completa

Detalles Bibliográficos
Autores principales: Satoh, Shunpei, Takatori, Atsushi, Ogura, Atsushi, Kohashi, Kenichi, Souzaki, Ryota, Kinoshita, Yoshiaki, Taguchi, Tomoaki, Hossain, Md. Shamim, Ohira, Miki, Nakamura, Yohko, Nakagawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015029/
https://www.ncbi.nlm.nih.gov/pubmed/27604320
http://dx.doi.org/10.1038/srep32682