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Direct Optofluidic Measurement of the Lipid Permeability of Fluoroquinolones

Quantifying drug permeability across lipid membranes is crucial for drug development. In addition, reduced membrane permeability is a leading cause of antibiotic resistance in bacteria, and hence there is a need for new technologies that can quantify antibiotic transport across biological membranes....

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Detalles Bibliográficos
Autores principales: Cama, Jehangir, Schaich, Michael, Al Nahas, Kareem, Hernández-Ainsa, Silvia, Pagliara, Stefano, Keyser, Ulrich F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015079/
https://www.ncbi.nlm.nih.gov/pubmed/27604156
http://dx.doi.org/10.1038/srep32824