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Statins affect ETS1-overexpressing triple-negative breast cancer cells by restoring DUSP4 deficiency

We investigated the molecular mechanisms underlying statin-induced growth suppression of triple-negative breast cancer (TNBC) that overexpress the transcription factor ets proto-oncogene 1(ets-1) and downregulate dual specific protein phosphatase 4(dusp4) expression. We examined the gene expression...

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Detalles Bibliográficos
Autores principales: Jung, Hae Hyun, Lee, Soo-Hyeon, Kim, Ji-Yeon, Ahn, Jin Seok, Park, Yeon Hee, Im, Young-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015082/
https://www.ncbi.nlm.nih.gov/pubmed/27604655
http://dx.doi.org/10.1038/srep33035