NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation

The histone methyltransferase NSD2/WHSC1/MMSET is overexpressed in a number of solid tumors but its contribution to the biology of these tumors is not well understood. Here, we describe that NSD2 contributes to the proliferation of a subset of lung cancer cell lines by supporting oncogenic RAS trans...

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Detalles Bibliográficos
Autores principales: García-Carpizo, Verónica, Sarmentero, Jacinto, Han, Bomie, Graña, Osvaldo, Ruiz-Llorente, Sergio, Pisano, David G., Serrano, Manuel, Brooks, Harold B., Campbell, Robert M., Barrero, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015087/
https://www.ncbi.nlm.nih.gov/pubmed/27604143
http://dx.doi.org/10.1038/srep32952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015087/
https://www.ncbi.nlm.nih.gov/pubmed/27604143
http://dx.doi.org/10.1038/srep32952

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