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Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death, especially in China. And the mechanism of its progression remains poorly understood. Growing evidence indicates that long non-coding RNAs (lncRNAs) are found to be dysregulated in many cancers, including...

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Detalles Bibliográficos
Autores principales: Huang, Ming-de, Chen, Wen-ming, Qi, Fu-zhen, Xia, Rui, Sun, Ming, Xu, Tong-peng, Yin, Li, Zhang, Er-bao, De, Wei, Shu, Yong-qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015197/
https://www.ncbi.nlm.nih.gov/pubmed/27391317
http://dx.doi.org/10.1186/s13045-015-0153-1