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MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease

BACKGROUND: MicroRNAs (miRNAs) are noncoding RNAs that modulate cellular gene expression, primarily at the post-transcriptional level. We sought to examine the functional role of miR-155 in a model of viral-induced neuroinflammation. METHODS: Acute encephalomyelitis and immune-mediated demyelination...

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Detalles Bibliográficos
Autores principales: Dickey, Laura L., Worne, Colleen L., Glover, Jessica L., Lane, Thomas E., O’Connell, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015201/
https://www.ncbi.nlm.nih.gov/pubmed/27604627
http://dx.doi.org/10.1186/s12974-016-0699-z