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Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics

BACKGROUND: Epidermal growth factor receptor (EGFR) mutation-induced drug resistance is a difficult problem in lung cancer treatment. Studying the molecular mechanisms of drug resistance can help to develop corresponding treatment strategies and benefit new drug design. METHODS: In this study, Roset...

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Detalles Bibliográficos
Autores principales: Ma, Lichun, Zou, Bin, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015241/
https://www.ncbi.nlm.nih.gov/pubmed/27610045
http://dx.doi.org/10.1186/s12953-016-0102-0