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Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics
BACKGROUND: Epidermal growth factor receptor (EGFR) mutation-induced drug resistance is a difficult problem in lung cancer treatment. Studying the molecular mechanisms of drug resistance can help to develop corresponding treatment strategies and benefit new drug design. METHODS: In this study, Roset...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015241/ https://www.ncbi.nlm.nih.gov/pubmed/27610045 http://dx.doi.org/10.1186/s12953-016-0102-0 |