Characterization of a pathway-specific activator of milbemycin biosynthesis and improved milbemycin production by its overexpression in Streptomyces bingchenggensis

BACKGROUND: Milbemycins, a group of 16-membered macrolides with potent anthelminthic and insecticidal activity, are produced by several Streptomyces and used widely in agricultural, medical and veterinary fields. Milbemycin A3 and A4, the main components produced by Streptomyces bingchenggensis, hav...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, He, Hairong, Liu, Hui, Wang, Haiyan, Wang, Xiangjing, Xiang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015266/
https://www.ncbi.nlm.nih.gov/pubmed/27604457
http://dx.doi.org/10.1186/s12934-016-0552-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015266/
https://www.ncbi.nlm.nih.gov/pubmed/27604457
http://dx.doi.org/10.1186/s12934-016-0552-1

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