Critical Role of Coaptive Strain in Aortic Valve Leaflet Homeostasis: Use of a Novel Flow Culture Bioreactor to Explore Heart Valve Mechanobiology

BACKGROUND: Aortic valve (AV) disease presents critical situations requiring surgery in over 2% of the US population and is increasingly the reason for cardiac surgery. Throughout the AV cycle, mechanical forces of multiple types and varying intensities are exerted on valve leaflets. The mechanisms...

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Detalles Bibliográficos
Autores principales: Maeda, Katsuhide, Ma, Xiaoyuan, Hanley, Frank L., Riemer, R. Kirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015277/
https://www.ncbi.nlm.nih.gov/pubmed/27464792
http://dx.doi.org/10.1161/JAHA.116.003506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015277/
https://www.ncbi.nlm.nih.gov/pubmed/27464792
http://dx.doi.org/10.1161/JAHA.116.003506

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