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ABT‐719 for the Prevention of Acute Kidney Injury in Patients Undergoing High‐Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial

BACKGROUND: Patients undergoing cardiac surgeries with cardiopulmonary bypass (on‐pump) have a high risk for acute kidney injury (AKI). We tested ABT‐719, a novel α‐melanocyte‐stimulating hormone analog, for prevention of AKI in postoperative cardiac surgery patients. METHODS AND RESULTS: This phase...

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Detalles Bibliográficos
Autores principales: McCullough, Peter A., Bennett‐Guerrero, Elliott, Chawla, Lakhmir S., Beaver, Thomas, Mehta, Ravindra L., Molitoris, Bruce A., Eldred, Ann, Ball, Greg, Lee, Ho‐Jin, Houser, Mark T., Khan, Samina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015281/
https://www.ncbi.nlm.nih.gov/pubmed/27543797
http://dx.doi.org/10.1161/JAHA.116.003549