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Genetic Abrogation of Adenosine A(3) Receptor Prevents Uninephrectomy and High Salt–Induced Hypertension

BACKGROUND: Early‐life reduction in nephron number (uninephrectomy [UNX]) and chronic high salt (HS) intake increase the risk of hypertension and chronic kidney disease. Adenosine signaling via its different receptors has been implicated in modulating renal, cardiovascular, and metabolic functions a...

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Detalles Bibliográficos
Autores principales: Yang, Ting, Zollbrecht, Christa, Winerdal, Malin E., Zhuge, Zhengbing, Zhang, Xing‐Mei, Terrando, Niccolo, Checa, Antonio, Sällström, Johan, Wheelock, Craig E., Winqvist, Ola, Harris, Robert A., Larsson, Erik, Persson, A. Erik G., Fredholm, Bertil B., Carlström, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015411/
https://www.ncbi.nlm.nih.gov/pubmed/27431647
http://dx.doi.org/10.1161/JAHA.116.003868