Endothelin‐1 Drives Epithelial‐Mesenchymal Transition in Hypertensive Nephroangiosclerosis

BACKGROUND: Tubulointerstitial fibrosis, the final outcome of most kidney diseases, involves activation of epithelial mesenchymal transition (EMT). Endothelin‐1 (ET‐1) activates EMT in cancer cells, but it is not known whether it drives EMT in the kidney. We therefore tested the hypothesis that tubu...

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Detalles Bibliográficos
Autores principales: Seccia, Teresa M., Caroccia, Brasilina, Gioco, Francesca, Piazza, Maria, Buccella, Valentina, Guidolin, Diego, Guerzoni, Eugenia, Montini, Barbara, Petrelli, Lucia, Pagnin, Elisa, Ravarotto, Verdiana, Belloni, Anna S., Calò, Lorenzo A., Rossi, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015413/
https://www.ncbi.nlm.nih.gov/pubmed/27444511
http://dx.doi.org/10.1161/JAHA.116.003888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015413/
https://www.ncbi.nlm.nih.gov/pubmed/27444511
http://dx.doi.org/10.1161/JAHA.116.003888

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