Cargando…

Restoring immune tolerance in neuromyelitis optica: Part I

Neuromyelitis optica (NMO) and spectrum disorder (NMO/SD) represent a vexing process and its clinical variants appear to have at their pathogenic core the loss of immune tolerance to the aquaporin-4 water channel protein. This process results in a characteristic pattern of astrocyte dysfunction, los...

Descripción completa

Detalles Bibliográficos
Autores principales: Steinman, Larry, Bar-Or, Amit, Behne, Jacinta M., Benitez-Ribas, Daniel, Chin, Peter S., Clare-Salzler, Michael, Healey, Donald, Kim, James I., Kranz, David M., Lutterotti, Andreas, Martin, Roland, Schippling, Sven, Villoslada, Pablo, Wei, Cheng-Hong, Weiner, Howard L., Zamvil, Scott S., Yeaman, Michael R., Smith, Terry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015539/
https://www.ncbi.nlm.nih.gov/pubmed/27648463
http://dx.doi.org/10.1212/NXI.0000000000000276