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Integrating Domain Specific Knowledge and Network Analysis to Predict Drug Sensitivity of Cancer Cell Lines

One of fundamental challenges in cancer studies is that varying molecular characteristics of different tumor types may lead to resistance to certain drugs. As a result, the same drug can lead to significantly different results in different types of cancer thus emphasizing the need for individualized...

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Detalles Bibliográficos
Autores principales: Kim, Sebo, Sundaresan, Varsha, Zhou, Lei, Kahveci, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015856/
https://www.ncbi.nlm.nih.gov/pubmed/27607242
http://dx.doi.org/10.1371/journal.pone.0162173