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A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation

The nonmethylable cytosine analogs, 5-azacytidine and zebularine, are widely used to inhibit DNA methyltransferase activity and reduce genomic DNA methylation. In this study, whole-genome bisulfite sequencing is used to construct maps of DNA methylation with single base pair resolution in Arabidopsi...

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Detalles Bibliográficos
Autores principales: Griffin, Patrick T., Niederhuth, Chad E., Schmitz, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015934/
https://www.ncbi.nlm.nih.gov/pubmed/27402357
http://dx.doi.org/10.1534/g3.116.030262