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Ligand-Bound GeneSwitch Causes Developmental Aberrations in Drosophila that Are Alleviated by the Alternative Oxidase

Culture of Drosophila expressing the steroid-dependent GeneSwitch transcriptional activator under the control of the ubiquitous α-tubulin promoter was found to produce extensive pupal lethality, as well as a range of dysmorphic adult phenotypes, in the presence of high concentrations of the inducing...

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Detalles Bibliográficos
Autores principales: Andjelković, Ana, Kemppainen, Kia K., Jacobs, Howard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015941/
https://www.ncbi.nlm.nih.gov/pubmed/27412986
http://dx.doi.org/10.1534/g3.116.030882