Acute and Chronic Hyperglycemia Elicit JIP1/JNK-Mediated Endothelial Vasodilator Dysfunction of Retinal Arterioles

PURPOSE: Hyperglycemia, a hallmark of diabetes mellitus, is associated with retinal inflammation and impairment of endothelium-dependent nitric oxide (NO)–mediated dilation of retinal arterioles. However, molecular mechanisms involved in this diminished endothelial vasodilator function remain unclea...

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Detalles Bibliográficos
Autores principales: Hein, Travis W., Xu, Wenjuan, Xu, Xin, Kuo, Lih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015966/
https://www.ncbi.nlm.nih.gov/pubmed/27556216
http://dx.doi.org/10.1167/iovs.16-19990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015966/
https://www.ncbi.nlm.nih.gov/pubmed/27556216
http://dx.doi.org/10.1167/iovs.16-19990

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