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Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture

Stem cell-derived inner ear sensory epithelia are a promising source of tissues for treating patients with hearing loss and dizziness. We recently demonstrated how to generate inner ear sensory epithelia, designated as inner ear organoids, from mouse embryonic stem cells (ESCs) in a self-organizing...

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Detalles Bibliográficos
Autores principales: DeJonge, Rachel E., Liu, Xiao-Ping, Deig, Christopher R., Heller, Stefan, Koehler, Karl R., Hashino, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015985/
https://www.ncbi.nlm.nih.gov/pubmed/27607106
http://dx.doi.org/10.1371/journal.pone.0162508