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Characterization of a Novel Endoplasmic Reticulum Protein Involved in Tubercidin Resistance in Leishmania major

BACKGROUND: Tubercidin (TUB) is a toxic adenosine analog with potential antiparasitic activity against Leishmania, with mechanism of action and resistance that are not completely understood. For understanding the mechanisms of action and identifying the potential metabolic pathways affected by this...

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Detalles Bibliográficos
Autores principales: Aoki, Juliana Ide, Coelho, Adriano Cappellazzo, Muxel, Sandra Marcia, Zampieri, Ricardo Andrade, Sanchez, Eduardo Milton Ramos, Nerland, Audun Helge, Floeter-Winter, Lucile Maria, Cotrim, Paulo Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015992/
https://www.ncbi.nlm.nih.gov/pubmed/27606425
http://dx.doi.org/10.1371/journal.pntd.0004972