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Characterization of a Novel Endoplasmic Reticulum Protein Involved in Tubercidin Resistance in Leishmania major
BACKGROUND: Tubercidin (TUB) is a toxic adenosine analog with potential antiparasitic activity against Leishmania, with mechanism of action and resistance that are not completely understood. For understanding the mechanisms of action and identifying the potential metabolic pathways affected by this...
Autores principales: | Aoki, Juliana Ide, Coelho, Adriano Cappellazzo, Muxel, Sandra Marcia, Zampieri, Ricardo Andrade, Sanchez, Eduardo Milton Ramos, Nerland, Audun Helge, Floeter-Winter, Lucile Maria, Cotrim, Paulo Cesar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015992/ https://www.ncbi.nlm.nih.gov/pubmed/27606425 http://dx.doi.org/10.1371/journal.pntd.0004972 |
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