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Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium

Cytomegalovirus (CMV) infection elicits a very strong and sustained intravascular T cell immune response which may contribute towards development of accelerated immune senescence and vascular disease in older people. Virus-specific CD8+ T cell responses have been investigated extensively through the...

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Detalles Bibliográficos
Autores principales: Pachnio, Annette, Ciaurriz, Miriam, Begum, Jusnara, Lal, Neeraj, Zuo, Jianmin, Beggs, Andrew, Moss, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015996/
https://www.ncbi.nlm.nih.gov/pubmed/27606804
http://dx.doi.org/10.1371/journal.ppat.1005832