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Protective Role of Silymarin on Hepatic and Renal Toxicity Induced by MTX Based Chemotherapy in Children with Acute Lymphoblastic Leukemia

BACKGROUND: ALL is the most common childhood malignancy. The children with ALL are treated with methotrexate (MTX) based chemotherapy protocols. MTX causes unpredictable serious hepatic and renal side effects. Silymarin has antioxidant and anti-inflammatory activities and stimulates tissue regenerat...

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Detalles Bibliográficos
Autores principales: Hagag, Adel A., Elgamsy, Mohamed A., El-Asy, Hassan M., Mabrouk, Maaly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016017/
https://www.ncbi.nlm.nih.gov/pubmed/27648206
http://dx.doi.org/10.4084/MJHID.2016.043