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Anti-Drug Antibodies, Drug Levels, Interleukin-6 and Soluble TNF Receptors in Rheumatoid Arthritis Patients during the First 6 Months of Treatment with Adalimumab or Infliximab: A Descriptive Cohort Study

OBJECTIVES: With the present study we wanted to explore the impact of treatment with a tumor necrosis factor-α -inhibitor (TNFi) on levels of soluble biomarkers in rheumatoid arthritis (RA) patients and to identify predictors of impaired drug levels and development of anti-TNFi antibodies (anti-TNFi...

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Detalles Bibliográficos
Autores principales: Eng, Grith Petersen, Bouchelouche, Pierre, Bartels, Else Marie, Bliddal, Henning, Bendtzen, Klaus, Stoltenberg, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016088/
https://www.ncbi.nlm.nih.gov/pubmed/27606615
http://dx.doi.org/10.1371/journal.pone.0162316