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B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production

A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced “natural” IgM. Natural IgM is constitutively produced, even in the absence...

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Detalles Bibliográficos
Autor principal: Baumgarth, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016532/
https://www.ncbi.nlm.nih.gov/pubmed/27667991
http://dx.doi.org/10.3389/fimmu.2016.00324