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B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production
A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced “natural” IgM. Natural IgM is constitutively produced, even in the absence...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016532/ https://www.ncbi.nlm.nih.gov/pubmed/27667991 http://dx.doi.org/10.3389/fimmu.2016.00324 |