Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

AIMS/HYPOTHESIS: Intra-islet and gut–islet crosstalk are critical in orchestrating basal and postprandial metabolism. The aim of this study was to identify regulatory proteins and receptors underlying somatostatin secretion though the use of transcriptomic comparison of purified murine alpha, beta a...

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Detalles Bibliográficos
Autores principales: Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016554/
https://www.ncbi.nlm.nih.gov/pubmed/27390011
http://dx.doi.org/10.1007/s00125-016-4033-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016554/
https://www.ncbi.nlm.nih.gov/pubmed/27390011
http://dx.doi.org/10.1007/s00125-016-4033-1

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