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Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy

AIMS/HYPOTHESIS: Intra-retinal extravasation and modification of LDL have been implicated in diabetic retinopathy: autophagy may mediate these effects. METHODS: Immunohistochemistry was used to detect autophagy marker LC3B in human and murine diabetic and non-diabetic retinas. Cultured human retinal...

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Detalles Bibliográficos
Autores principales: Fu, Dongxu, Yu, Jeremy Y., Yang, Shihe, Wu, Mingyuan, Hammad, Samar M., Connell, Anna R., Du, Mei, Chen, Junping, Lyons, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016562/
https://www.ncbi.nlm.nih.gov/pubmed/27475954
http://dx.doi.org/10.1007/s00125-016-4058-5