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CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells

High density lipoprotein (HDL) has been proposed to be internalized and to promote reverse cholesterol transport in endothelial cells (ECs). However, the mechanism underlying these processes has not been studied. In this study, we aim to characterize HDL internalization and cholesterol efflux in ECs...

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Detalles Bibliográficos
Autores principales: Sun, Run-Lu, Huang, Can-Xia, Bao, Jin-Lan, Jiang, Jie-Yu, Zhang, Bo, Zhou, Shu-Xian, Cai, Wei-Bin, Wang, Hong, Wang, Jing-Feng, Zhang, Yu-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016689/
https://www.ncbi.nlm.nih.gov/pubmed/27458015
http://dx.doi.org/10.1074/jbc.M116.714279