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Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade

Bmps are morphogens involved in various gastric cellular functions. Studies in genetically-modified mice have shown that Bmp disruption in gastric epithelial and stromal cell compartments leads to the development of tumorigenesis. Our studies have demonstrated that abrogation of gastric epithelial B...

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Detalles Bibliográficos
Autores principales: Roy, Sébastien A. B., Allaire, Joannie M., Ouellet, Camille, Maloum-Rami, Faiza, Pomerleau, Véronique, Lemieux, Étienne, Babeu, Jean-Philippe, Rousseau, Jasmin, Paquet, Marilène, Garde-Granger, Perrine, Boudreau, François, Perreault, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016723/
https://www.ncbi.nlm.nih.gov/pubmed/27609464
http://dx.doi.org/10.1038/srep32759