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Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines

Oxaliplatin displays a wide spectrum of antitumor activities and is widely used in the treatment of metastatic colorectal cancer (CRC). However, tumor responses to this agent are variable, and the underlying mechanisms are poorly understood. In the present study, oxaliplatin was found to strongly in...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Zhou, Qian, Li, Minle, Tong, Xuemei, Sun, Jiayi, Qing, Yin, Sun, Liya, Yang, Xuhan, Hu, Xiaowen, Jiang, Jie, Yan, Xiaomei, He, Lin, Wan, Chunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016804/
https://www.ncbi.nlm.nih.gov/pubmed/27609465
http://dx.doi.org/10.1038/srep33078