Paeoniflorin Potentiates the Inhibitory Effects of Erlotinib in Pancreatic Cancer Cell Lines by Reducing ErbB3 Phosphorylation

Blockade of the epidermal growth factor receptor (EGFR) by EGFR tyrosine kinase inhibitors is insufficient for effective anti-tumor activity because the reactivation of the ErbB3 signaling pathway significantly contributes to activating the consequent phosphoinositide 3-kinase (PI3K)/Akt signaling p...

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Detalles Bibliográficos
Autores principales: Hao, Jian, Yang, Xue, Ding, Xiu-li, Guo, Lei-ming, Zhu, Cui-hong, Ji, Wei, Zhou, Tong, Wu, Xiong-zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016851/
https://www.ncbi.nlm.nih.gov/pubmed/27609096
http://dx.doi.org/10.1038/srep32809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016851/
https://www.ncbi.nlm.nih.gov/pubmed/27609096
http://dx.doi.org/10.1038/srep32809

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