Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa

Lipid A (also known as endotoxin) is the hydrophobic portion of lipopolysaccharides. It is an essential membrane component required for the viability of gram-negative bacteria. The enzymes involved in its biosynthesis are attractive targets for the development of novel antibiotics. LpxH catalyzes th...

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Detalles Bibliográficos
Autores principales: Okada, Chiaki, Wakabayashi, Hiroko, Kobayashi, Momoko, Shinoda, Akira, Tanaka, Isao, Yao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016852/
https://www.ncbi.nlm.nih.gov/pubmed/27609419
http://dx.doi.org/10.1038/srep32822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016852/
https://www.ncbi.nlm.nih.gov/pubmed/27609419
http://dx.doi.org/10.1038/srep32822

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