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Structure-function analysis of Avian β-defensin-6 and β-defensin-12: role of charge and disulfide bridges

BACKGROUND: Avian beta-defensins (AvBD) are small, cationic, antimicrobial peptides. The potential application of AvBDs as alternatives to antibiotics has been the subject of interest. However, the mechanisms of action remain to be fully understood. The present study characterized the structure-func...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Zhang, Chunye, Zhang, Xuehan, Zhang, Michael Z., Rottinghaus, George E., Zhang, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016922/
https://www.ncbi.nlm.nih.gov/pubmed/27613063
http://dx.doi.org/10.1186/s12866-016-0828-y