Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

BACKGROUND: Glycyrrhizin (Gly) protects against brain injury induced by stroke. We studied whether Gly achieves its protection by inhibiting T cell activity and high-mobility group box 1 (HMGB1) release in the ischemic brain. METHODS: Stroke was induced by transient middle cerebral artery occlusion...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Xiaoxing, Gu, Lijuan, Wang, Yan, Luo, Ying, Zhang, Hongfei, Lee, Jessica, Krams, Sheri, Zhu, Shengmei, Zhao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016958/
https://www.ncbi.nlm.nih.gov/pubmed/27609334
http://dx.doi.org/10.1186/s12974-016-0705-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016958/
https://www.ncbi.nlm.nih.gov/pubmed/27609334
http://dx.doi.org/10.1186/s12974-016-0705-5

Ejemplares similares