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Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

BACKGROUND: Glycyrrhizin (Gly) protects against brain injury induced by stroke. We studied whether Gly achieves its protection by inhibiting T cell activity and high-mobility group box 1 (HMGB1) release in the ischemic brain. METHODS: Stroke was induced by transient middle cerebral artery occlusion...

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Detalles Bibliográficos
Autores principales:	Xiong, Xiaoxing, Gu, Lijuan, Wang, Yan, Luo, Ying, Zhang, Hongfei, Lee, Jessica, Krams, Sheri, Zhu, Shengmei, Zhao, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016958/ https://www.ncbi.nlm.nih.gov/pubmed/27609334 http://dx.doi.org/10.1186/s12974-016-0705-5

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