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Type I interferon responses are impaired in latently HIV infected cells

BACKGROUND: The latent HIV-1 reservoir represents the primary barrier to the eradication of HIV-1 infection. The design of novel reservoir-clearance strategies, however, is impeded in part by the inability to distinguish latently HIV-infected cells from uninfected cells. Significant impairment of th...

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Detalles Bibliográficos
Autores principales: Ranganath, Nischal, Sandstrom, Teslin S., Fadel, Saleh, Côté, Sandra C., Angel, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017046/
https://www.ncbi.nlm.nih.gov/pubmed/27613235
http://dx.doi.org/10.1186/s12977-016-0302-9