IL-1β induces IL-6 production and increases invasiveness and estrogen-independent growth in a TG2-dependent manner in human breast cancer cells

BACKGROUND: We previously reported that IL-6 and transglutaminase 2 (TG2) were expressed in more aggressive basal-like breast cancer cells, and TG2 and IL-6 expression gave these cells stem-cell-like phenotypes, increased invasive ability, and increased metastatic potential. In the present study, th...

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Detalles Bibliográficos
Autores principales: Oh, Keunhee, Lee, Ok-Young, Park, Yeonju, Seo, Myung Won, Lee, Dong-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017052/
https://www.ncbi.nlm.nih.gov/pubmed/27609180
http://dx.doi.org/10.1186/s12885-016-2746-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017052/
https://www.ncbi.nlm.nih.gov/pubmed/27609180
http://dx.doi.org/10.1186/s12885-016-2746-7

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