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Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response

Mitochondria, which are essential organelles in resting and replicating cells, can vary in number, mass and shape. Past research has primarily focused on short-term molecular mechanisms underlying fission/fusion. Less is known about longer-term mitochondrial behavior such as the overall makeup of ce...

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Detalles Bibliográficos
Autores principales: Giedt, Randy J., Fumene Feruglio, Paolo, Pathania, Divya, Yang, Katherine S., Kilcoyne, Aoife, Vinegoni, Claudio, Mitchison, Timothy J., Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017129/
https://www.ncbi.nlm.nih.gov/pubmed/27609668
http://dx.doi.org/10.1038/srep32985