Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

Polysialic acid (polySia) is a unique carbohydrate polymer expressed on the surface of NCAM (neuronal cell adhesion molecule) in a number of cancers where it modulates cell-cell and cell-matrix adhesion, migration, invasion and metastasis and is strongly associated with poor clinical prognosis. We h...

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Detalles Bibliográficos
Autores principales: Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017143/
https://www.ncbi.nlm.nih.gov/pubmed/27611649
http://dx.doi.org/10.1038/srep33026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017143/
https://www.ncbi.nlm.nih.gov/pubmed/27611649
http://dx.doi.org/10.1038/srep33026

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