Molecular mechanism of male differentiation is conserved in the SRY-absent mammal, Tokudaia osimensis

The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation...

Descripción completa

Detalles Bibliográficos
Autores principales: Otake, Tomofumi, Kuroiwa, Asato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017195/
https://www.ncbi.nlm.nih.gov/pubmed/27611740
http://dx.doi.org/10.1038/srep32874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017195/
https://www.ncbi.nlm.nih.gov/pubmed/27611740
http://dx.doi.org/10.1038/srep32874

Ejemplares similares