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Molecular mechanism of male differentiation is conserved in the SRY-absent mammal, Tokudaia osimensis
The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017195/ https://www.ncbi.nlm.nih.gov/pubmed/27611740 http://dx.doi.org/10.1038/srep32874 |