Exchange factors directly activated by cAMP mediate melanocortin 4 receptor-induced gene expression

G(s) protein-coupled receptors regulate many vital body functions by activation of cAMP response elements (CRE) via cAMP-dependent kinase A (PKA)-mediated phosphorylation of the CRE binding protein (CREB). Melanocortin 4 receptors (MC4R) are prototypical G(s)-coupled receptors that orchestrate the h...

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Detalles Bibliográficos
Autores principales: Glas, Evi, Mückter, Harald, Gudermann, Thomas, Breit, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017209/
https://www.ncbi.nlm.nih.gov/pubmed/27612207
http://dx.doi.org/10.1038/srep32776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017209/
https://www.ncbi.nlm.nih.gov/pubmed/27612207
http://dx.doi.org/10.1038/srep32776

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