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Exchange factors directly activated by cAMP mediate melanocortin 4 receptor-induced gene expression
G(s) protein-coupled receptors regulate many vital body functions by activation of cAMP response elements (CRE) via cAMP-dependent kinase A (PKA)-mediated phosphorylation of the CRE binding protein (CREB). Melanocortin 4 receptors (MC4R) are prototypical G(s)-coupled receptors that orchestrate the h...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017209/ https://www.ncbi.nlm.nih.gov/pubmed/27612207 http://dx.doi.org/10.1038/srep32776 |