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Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study

Sorafenib is the only chemotherapeutic agent currently approved for unresectable hepatocellular carcinoma (HCC). However, poor response rates have been widely reported. Indole-3-carbinol (I3C) is a potential chemopreventive phytochemical. The present study aimed to explore the potential chemomodulat...

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Detalles Bibliográficos
Autores principales: Abdelmageed, Mai M., El-Naga, Reem N., El-Demerdash, Ebtehal, Elmazar, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017213/
https://www.ncbi.nlm.nih.gov/pubmed/27612096
http://dx.doi.org/10.1038/srep32733