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MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle

The restriction point marks a switch in G1 from growth factor-dependent to growth factor-independent progression of the cell cycle. The proper regulation of this switch is important for normal cell processes; aberrations could result in a number of diseases such as cancer, neurodegenerative disorder...

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Detalles Bibliográficos
Autores principales: del Rosario, Ricardo C. H., Damasco, Joseph Ray Clarence G., Aguda, Baltazar D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017317/
https://www.ncbi.nlm.nih.gov/pubmed/27610602
http://dx.doi.org/10.1038/srep32823