Cargando…

The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling

OBJECTIVES: To study the role of the Rho/ROCK pathway in Ang II and TGF-β1-induced atrial remodeling. METHODS AND RESULTS: A canine atrial fibrillation (AF) model was established by rapid atrial pacing (RAP) of the left atrium. The roles of TGF-β1, the RhoA/ROCK signaling pathway and connective tiss...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li-Juan, Yao, Feng-Juan, Lu, Gui-Hua, Xu, Cheng-Gui, Xu, Zhe, Tang, Kai, Cheng, Yun-Jiu, Gao, Xiu-Ren, Wu, Su-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017578/
https://www.ncbi.nlm.nih.gov/pubmed/27611832
http://dx.doi.org/10.1371/journal.pone.0161625