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Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress
Thermal ablative therapies are important treatment options in the multidisciplinary care of patients with hepatocellular carcinoma (HCC), but lesions larger than 2–3 cm are plagued with high local recurrence rates and overall survival of these patients remains poor. Currently no adjuvant therapies e...
Autores principales: | Thompson, Scott M., Callstrom, Matthew R., Jondal, Danielle E., Butters, Kim A., Knudsen, Bruce E., Anderson, Jill L., Lien, Karen R., Sutor, Shari L., Lee, Ju-Seog, Thorgeirsson, Snorri S., Grande, Joseph P., Roberts, Lewis R., Woodrum, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017586/ https://www.ncbi.nlm.nih.gov/pubmed/27611696 http://dx.doi.org/10.1371/journal.pone.0162634 |
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