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Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis

Two of the most common myeloid malignancies, myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), are associated with exceedingly low survival rates despite recent therapeutic advances. While their etiology is not completely understood, evidence suggests that certain chromosomal abnormal...

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Detalles Bibliográficos
Autores principales: Arcipowski, Kelly M., Bulic, Marinka, Gurbuxani, Sandeep, Licht, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017600/
https://www.ncbi.nlm.nih.gov/pubmed/27610619
http://dx.doi.org/10.1371/journal.pone.0162515