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Oral Delivery of Pentameric Glucagon-Like Peptide-1 by Recombinant Lactobacillus in Diabetic Rats

Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by intestinal cells and stimulates insulin secretion from the pancreas in a glucose-dependent manner. Exogenously supplied GLP-1 analogues are used in the treatment of type 2 diabetes. An anti-diabetic effect of Lactobacillus in lowerin...

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Detalles Bibliográficos
Autores principales: Lin, Yin, Krogh-Andersen, Kasper, Pelletier, Julien, Marcotte, Harold, Östenson, Claes-Göran, Hammarström, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017604/
https://www.ncbi.nlm.nih.gov/pubmed/27610615
http://dx.doi.org/10.1371/journal.pone.0162733